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With so many, and so many cost-free, options to network and to distribute your messages, you can now amortize the cost of those efforts that aren't cost-free--website development; literature writing, design, and printing; or exhibit booth development, for example--across more applications. "yet another knee implant", or do you want them thinking "reproducible surgical technique" or "happy patients, returning to their normal, active lifestyle. Don't get hung up on the "edifice complex"--many outstanding agencies have very modest offices.  Stop by my web blog ::  http://www.schuttingen-tuinhout.nl/